Sperm Fragmentation Test for men
Sperm DNA fragmentation (Sperm DNA fragmentation - SDF) is a condition of damage to the genetic structure of sperm, specifically internal DNA breaks, accounting for about 20% of male infertility cases. However, this abnormality cannot be detected through semen analysis. Therefore, determining the level of sperm DNA fragmentation is essential to determine the cause of infertility in men.
In recent years, tests to evaluate sperm DNA fragmentation index (DFI) have become increasingly popular around the world. In particular, the sperm chromatin structure assessment test (Sperm Chromatin Structure Assay-SCSA) is considered the "Gold standard" in assessing sperm DNA fragmentation and is widely used at many centers. In Vitro Fertilisation.
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Morals of Sperm fragmentation test
Determining the level of sperm DNA fragmentation helps obstetricians provide appropriate advice and treatment regimens for infertile couples.
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Who should take Sperm fragmentation test
+ Couples with a history of miscarriage or consecutive stillbirths (2 times or more), fetal malformations
+ People whose semen test showed low sperm count or normal shape
+ Couples are considering IUI, IVF, ICSI
+ Men over 40 years old
+ Men smoke.
+ Men take certain medications that can affect sperm
+ Men who have been treated for cancer
+ Men exposed to toxic agents
+ Men with urinary tract infections
+ Men are considering treatment for varicocele
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Sperm fragmentation test at Phacolab
1. Principle: Based on the sperm chromatin structure assessment test (Sperm Chromatin Structure Assay - SCSA) to evaluate sperm DNA fragmentation, based on the different fluorescence of broken DNA segments broken and intact DNA fragments with Acridine orange (AO), measured by flow cytometer.
2. Time for results: 4 hours from the time of sample receipt
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