Thrombophilia test analyzes DNA mutations which cause blood clotting disorders
What is Thrombophilia?
Thrombophilia (or hypercoagulable syndrome) is defined as a group of inherited or acquired disorders, characterized by a higher than normal tendency to form blood clots. Consequences include venous thromboembolism (VTE), disseminated intravascular coagulation (DIC), arterial thrombosis...
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What causes Thrombophilia?
Thrombophilia syndrome can occur due to:
- Chromosomal abnormalities
- Uterine abnormalities
- Endometrial infection
- Endocrine abnormalities
- Antiphospholipid syndrome
- Hereditary thrombophilia
- Allergy
- Genetic factors
- Exposure to environmental factors and stressors
*In particular, pregnancy is inherently a physiologically hyperactive process for women, combined with Thrombophilia syndrome, which increases thrombosis, leading to many dangerous complications.
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Who should test for Thrombophilia?
Thrombophilia testing is needed if:
- Women with a history of recurrent miscarriage or stillbirth
- Pregnant women show signs of poor fetal development.
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Testing for Thrombophilia at Phacolab
1. Equipment: CFX 96™ Realtime System
2. Technology: Realtime PCR
3. Chemicals: Thrombophilia Multiplex Realtime PCR Kit A (8 mutations)
4. Samples:
- Whole blood sample
- Hair with roots
- Collect saliva sample
- Take nail samples
5. Time for results:
6. Sensitivity/specificity:
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